Colloidal magnetic nanoparticles for personalized theranostics in oncology: advanced in-situ x-ray spectroscopic and x-ray nano-imaging research.

From 06.05.2016 till 31.12.2017
Grant holder: Alexander Soldatov
Responsible: Mikhail Soldatov
Workers: Yulia Podkovirina, Maria Kremennaya, Tatiana Lastovina, Mikhail Soldatov, Oleg Polozhentsev, Elena Kuchma, Yulia Piminova, Yulia Polyakova, Kristina Vetlitsyna

Nanomedicine has become nowadays one of the most important research fields. Further development of novel advanced nanomaterials for biomedical applications is limited to great extent by the lack of cutting-edge characterization techniques of both nanoparticles themselves and their spatial distribution in biological tissues after administration. Magnetic nanoparticles for theranostics application in oncology (contrast agent for MRI (Magnetic Resonance Imaging) and active material for Magnetic Hyperthermia treatment) should be optimized in size, shape (and corresponding surface chemistry) and specific magnetic characteristics. A possibility of fine tuning of these nanoparticles characteristics could be a very important step towards personalized nanomedicine.